Newly Diagnosed

Metastatic OM

Resources

OM Registry

Education & Events

Metastatic Treatments

Scientific Papers

Possible treatments for you to discuss with your physician about which ones are right for you.  When you are discussing treatment plans, always check ahead to make sure that the treatment plan you looking to use will not disqualify you for a clinical trial in the future.  Having a next step treatment plan is a good way to be ready if your current treatment stops working.  Your physician can help you develop a treatment plan with next steps and possible clinical trials that are right for you.

Liver Directed therapy

Embolization – chemotherapy, radiation, immunotherapy

Regional isolation Perfusion

IHP HIA

IHP can only be done one, HIA PHP are less invasive and may be performed multiple times.

Isolated hepatic infusion (IHP), open surgical procedure involving vascular isolation of the liver with high doses of chemotherapy delivered directly to the liver.  Most commonly done with Mmelphalan

PHP double  ballon catheter inserted into the inferior vena cava to isolate the blood supply to the live and then is  filtered extracorporeally.   Better tolerated than IHP but reports are lacking efficacy results.

Hepatic chemoemolization  drug eluting beads, gelatin sponge, polyvinyl sponge, resorbable microspheres and polyvinyl alcohol particles. Chemoembolization has been well tolerated.

Hepatic immunoembolization

Immunologic stimulant into the hepatic artery followed by an emboli zing agent.

Hepatic Radioembolization or hepatic trans-arterial radioemboliztion (TARE) or selective internal RT (SIRT) glass or resin yttrium-90 needs are introduced to the hepatic artery.

There is also resection of the tumor that might be appropriate.  This is usually done when there are few tumors and are easily accessible.  Not all tumors can be resected.  Embolization might be done as well.

Immunotherapy is an option your physician might recommend

Aniti PD-1 mono therapy

Pembrolizumab

Nivolumab

Nivolumab/ipilimumab

Ipilimumab

Crytotoxic Regimens

Dacarbazine

Temozolomide

Paclitaxel

Albumin-bound Paclitaxel

Carboplatin//paclitaxel

Targeted Therapy

Trametinib

Tentafusp (IMCgp100) is only available from centers who participated in the clinical trial under special use.  Contact your physician if you would like more information. It is currently not FDA approved.

TIL

Dendritic Cell Vaccination

Clinical Trial Finder
clinicaltrials.gov
I have recently found myself in a second ‘nightmare’ phase of this horrible disease – discovering metastasis. I don’t know what I would have done without my friends at ACIS. They are always there for me, providing emotional and social support, valuable information and insight, and helping me feel that I am not alone on this journey. It’s truly a blessing to have my new friends to talk things over with, who understand what I’m going through, and help me develop a plan of action. I am so grateful for ACIS!
Sharon N, Farmington Hills, MI